Tissue Grinder, Potter-Elvehjem, with PTFE Pestle and Glass Tube, 10 ml KIMAX®

What is Potter-Elvehjem?

Rounded shape on the lower portion of the pestle (sometimes considered to be a Dounce style):

• sample is progressively ground smaller in the rounded section
• homogenate is produced as the sample is forced through the cylindrical section
• Does not provide as much grinding surface as the DUALL style because of the differences in the pestles’ tip shape (round vs. conical)
• Ground glass pestle versions are suited for connective tissues.
• PTFE pestle versions are used with softer tissues.

How to choose the correct tissue grinder?

1. Conically shaped pestles homogenise better than pestles with a rounded shape.
2. Ground glass to ground glass surfaces homogenize better than smooth glass to smooth glass or PTFE to smooth glass.

Using these two rules, a glass DUALL tissue grinder produces the finest homogenate while a glass Dounce will produce a relatively coarse homogenate.